| 别名 | ACTA1;ACTA;Actin;alpha skeletal muscle;Alpha-actin-1 |
| 基因名称 | ACTA1 |
| 蛋白名称 | Alpha skeletal muscle Actin |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P68133 |
| Mouse Gene ID | 11459 |
| Mouse Swissprot No. | P68134 |
| Rat Gene ID | 29437 |
| Rat Swissprot No. | P68136 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500-1:2000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200 |
| 参考分子量 | 42kDa |
| 预测分子量 | 42kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The product encoded by this gene belongs to the actin family of proteins , which are highly conserved proteins that play a role in cell motility , structure and integrity. Alpha , beta and gamma actin isoforms have been identified , with alpha actins being a major constituent of the contractile apparatus , while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3 , congenital myopathy with excess of thin myofilaments , congenital myopathy with cores , and congenital myopathy with fiber-type disproportion , diseases that lead to muscle fiber defects. [provided by RefSeq , Jul 2008] , |
| 细胞定位 | Cytoplasm , cytoskeleton. |
| 纯化 | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Clonality | Monoclonal |
| 细胞定位 | Cytoplasm , cytoskeleton. |