| 别名 | TRADD;Tumor necrosis factor receptor type 1-associated DEATH domain protein;TNFR1-associated DEATH domain protein;TNFRSF1A-associated via death domain |
| 基因名称 | TRADD |
| 蛋白名称 | Tumor necrosis factor receptor type 1-associated DEATH domain protein |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | Q15628 |
| Mouse Gene ID | 71609 |
| Mouse Swissprot No. | Q3U0V2 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200 |
| 参考分子量 | 34kDa |
| 预测分子量 | 34kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2 , reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2 , and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1 , and is involved in the Fas-induced cell death pathway. [provided by RefSeq , Jul 2008] , |
| 细胞定位 | Nucleus . Cytoplasm . Cytoplasm , cytoskeleton . Shuttles between the cytoplasm and the nucleus. . |
| 纯化 | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Clonality | Monoclonal |
| 细胞定位 | Nucleus . Cytoplasm . Cytoplasm , cytoskeleton . Shuttles between the cytoplasm and the nucleus. . |
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