| 别名 | ASCL1;ASH1;BHLHA46;HASH1;Achaete-scute homolog 1;ASH-1;hASH1;Class A basic helix-loop-helix protein 46;bHLHa46 |
| 基因名称 | ASCL1 |
| 蛋白名称 | Achaete-scute homolog 1 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P50553 |
| Mouse Gene ID | 17172 |
| Mouse Swissprot No. | Q02067 |
| Rat Gene ID | 64186 |
| Rat Swissprot No. | P19359 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:100-1:500;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000 |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | achaete-scute family bHLH transcription factor 1 (ASCL1) Homo sapiens This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3') . Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq , Jul 2008] , |
| 细胞定位 | Nucleus . |
| 纯化 | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Clonality | Monoclonal |
| 细胞定位 | Nucleus . |
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