| 别名 | CANPL1;PIG30 |
| 基因名称 | CAPN1 |
| 蛋白名称 | Calpain-1 catalytic subunit (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP) |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P07384 |
| Mouse Swissprot No. | O35350 |
| Rat Swissprot No. | P97571 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000;WB 1:500-1:2000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000 |
| 参考分子量 | 75kDa |
| 预测分子量 | 82kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The calpains , calcium-activated neutral proteases , are nonlysosomal , intracellular cysteine proteases. The mammalian calpains include ubiquitous , stomach-specific , and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large , catalytic subunits associated with a common small , regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme , calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq , Nov 2010] , |
| 细胞定位 | Cytoplasm . Cell membrane . Translocates to the plasma membrane upon Ca (2+) binding. In granular keratinocytes and in lower corneocytes , colocalizes with FLG and FLG2 (PubMed:21531719) . . |
| 纯化 | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Clonality | Monoclonal |
| 细胞定位 | Cytoplasm . Cell membrane . Translocates to the plasma membrane upon Ca (2+) binding. In granular keratinocytes and in lower corneocytes , colocalizes with FLG and FLG2 (PubMed:21531719) . . |
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