| 别名 | ATP6A1;ATP6V1A1;VPP2 |
| 基因名称 | ATP6V1A |
| 蛋白名称 | V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (V-ATPase 69 kDa subunit) (Vacuolar ATPase isoform VA68) (Vacuolar proton pump subunit alpha) |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P38606 |
| Mouse Swissprot No. | P50516 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200 |
| 参考分子量 | 68kDa |
| 预测分子量 | 68kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a component of vacuolar ATPase (V-ATPase) , a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting , zymogen activation , receptor-mediated endocytosis , and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits , two G subunits plus the C , D , E , F , and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a , c , c' , c" , and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all |
| 细胞定位 | Cytoplasm . Cytoplasm , cytosol . Cytoplasmic vesicle , secretory vesicle . Cytoplasmic vesicle , clathrin-coated vesicle membrane ; Peripheral membrane protein . Lysosome . Co-localizes with WFS1 in the secretory granules in neuroblastoma cell lines. . |
| 纯化 | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Clonality | Monoclonal |
| 细胞定位 | Cytoplasm . Cytoplasm , cytosol . Cytoplasmic vesicle , secretory vesicle . Cytoplasmic vesicle , clathrin-coated vesicle membrane ; Peripheral membrane protein . Lysosome . Co-localizes with WFS1 in the secretory granules in neuroblastoma cell lines. . |
周一至周日 8:00-18:00
