| 别名 | Polyphosphoinositide phosphatase;Phosphatidylinositol 3,5-bisphosphate 5-phosphatase;SAC domain-containing protein 3;KIAA0274;SAC3 |
| 基因名称 | FIG4 |
| 蛋白名称 | FIG4 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | Q92562 |
| Mouse Gene ID | 103199 |
| Mouse Swissprot No. | Q91WF7 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:100-1:500;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200 |
| 参考分子量 | 95kDa |
| 预测分子量 | 104kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain , approximately 400 amino acids in length and consisting of seven conserved motifs , has been shown to possess phosphoinositide phosphatase activity. The yeast homolog , Sac1p , is involved in the regulation of various phosphoinositides , and affects diverse cellular functions such as actin cytoskeleton organization , Golgi function , and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease , type 4J. [provided by RefSeq , Jul 2008] , |
| 细胞定位 | Endosome membrane . Localization requires VAC14 and PIKFYVE. . |
| 纯化 | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Clonality | Monoclonal |
| 细胞定位 | Endosome membrane . Localization requires VAC14 and PIKFYVE. . |
周一至周日 8:00-18:00
