| 别名 | SFN;HME1;14-3-3 protein sigma;Epithelial cell marker protein 1;Stratifin |
| 基因名称 | SFN |
| 蛋白名称 | 14-3-3 protein sigma |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P31947 |
| Mouse Gene ID | 55948 |
| Mouse Swissprot No. | O70456 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000 |
| 参考分子量 | 28kDa |
| 预测分子量 | 28kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners , usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17 , regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. ,function:p53-regulated inhibitor of G2/M progression. ,similarity:Belongs to the 14-3-3 family. ,subcellular location:May be secreted by a non-classical secretory pathway. ,subunit:Homodimer. Interacts with KRT17 (By similarity) . Found in a complex with XPO7 , EIF4A1 , ARHGAP1 , VPS26A , VPS29 , VPS35 and SFN. ,tissue specificity:Present mainly in tissues enriched in stratified squamous keratinising epithelium. , |
| 细胞定位 | Cytoplasm. Nucleus . Secreted. May be secreted by a non-classical secretory pathway. |
| 纯化 | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Clonality | Monoclonal |
| 细胞定位 | Cytoplasm. Nucleus . Secreted. May be secreted by a non-classical secretory pathway. |
周一至周日 8:00-18:00
