| 别名 | N2DL2;RAET1H;UNQ463/PRO791 |
| 基因名称 | ULBP2 |
| 蛋白名称 | NKG2D ligand 2 (N2DL-2) (NKG2DL2) (ALCAN-alpha) (Retinoic acid early transcript 1H) (UL16-binding protein 2) |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | Q9BZM5 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200 |
| 参考分子量 | 27kDa |
| 预测分子量 | 27kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety , or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6. [provided by RefSeq , Jul 2015] , |
| 细胞定位 | Cell membrane ; Lipid-anchor , GPI-anchor . Endoplasmic reticulum . Secreted . In CMV-infected fibroblasts , detected in the endoplasmic reticulum/cis-Golgi. . |
| 纯化 | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Clonality | Monoclonal |
| 细胞定位 | Cell membrane ; Lipid-anchor , GPI-anchor . Endoplasmic reticulum . Secreted . In CMV-infected fibroblasts , detected in the endoplasmic reticulum/cis-Golgi. . |