| 别名 | Histone H1.2;Histone H1c;Histone H1d;Histone H1s-1 |
| 基因名称 | H1-2/H1F2/HIST1H1C |
| 蛋白名称 | Histone H1.2 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P16403 |
| Mouse Swissprot No. | P15864 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000 |
| 参考分子量 | 32kDa |
| 预测分子量 | 21kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A , H2B , H3 , and H4) form an octamer , around which approximately 146 bp of DNA is wrapped in repeating units , called nucleosomes. The linker histone , H1 , interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq , Aug 2015] , |
| 细胞定位 | Nucleus . Chromosome . Mainly localizes in euchromatin. |
| 纯化 | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Clonality | Monoclonal |
| 细胞定位 | Nucleus . Chromosome . Mainly localizes in euchromatin. |