| 别名 | MAPKAPK2;MAP kinase-activated protein kinase 2;MAPK-activated protein kinase 2;MAPKAP kinase 2;MAPKAP-K2;MAPKAPK-2;MK-2;MK2 |
| 基因名称 | MAPKAPK2 |
| 蛋白名称 | MAP kinase-activated protein kinase 2 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P49137 |
| Mouse Gene ID | 17164 |
| Mouse Swissprot No. | P49138 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000 |
| 参考分子量 | 49kDa |
| 预测分子量 | 46kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase , this kinase is known to be involved in many cellular processes including stress and inflammatory responses , nuclear export , gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq , Jul 2008] , |
| 细胞定位 | Cytoplasm . Nucleus . Phosphorylation and subsequent activation releases the autoinhibitory helix , resulting in the export from the nucleus into the cytoplasm. |
| 纯化 | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Clonality | Monoclonal |
| 细胞定位 | Cytoplasm . Nucleus . Phosphorylation and subsequent activation releases the autoinhibitory helix , resulting in the export from the nucleus into the cytoplasm. |