| 别名 | APOA1;Apolipoprotein A-I;Apo-AI;ApoA-I;Apolipoprotein A1 |
| 基因名称 | APOA1 |
| 蛋白名称 | Apolipoprotein A-I |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P02647 |
| Mouse Swissprot No. | Q00623 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:4000-1:8000;WB 1:500-1:2000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200 |
| 参考分子量 | 25kDa |
| 预测分子量 | 31kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes apolipoprotein A-I , which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein , which promotes cholesterol efflux from tissues to the liver for excretion , and is a cofactor for lecithin cholesterolacyltransferase (LCAT) , an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies , including Tangier disease , and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants , at least one of which encodes a preproprotein. [provided by RefSeq , Dec 2015] , |
| 细胞定位 | Secreted. |
| 纯化 | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Clonality | Monoclonal |
| 细胞定位 | Secreted. |