| 别名 | BCAM;LU;MSK19;Basal cell adhesion molecule;Auberger B antigen;B-CAM cell surface glycoprotein;F8/G253 antigen;Lutheran antigen;Lutheran blood group glycoprotein;CD239 |
| 基因名称 | BCAM |
| 蛋白名称 | Basal cell adhesion molecule |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P50895 |
| Mouse Gene ID | 57278 |
| Mouse Swissprot No. | Q9R069 |
| Rat Gene ID | 78958 |
| Rat Swissprot No. | Q9ESS6 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:500-1:1000;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000 |
| 参考分子量 | 88kDa |
| 预测分子量 | 67kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes Lutheran blood group glycoprotein , a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein , laminin. The protein contains five extracellular immunoglobulin domains , a single transmembrane domain , and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype , Lu (a-b-) , of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq , May 2012] , |
| 细胞定位 | Membrane; Single-pass type I membrane protein. |
| 纯化 | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Clonality | Monoclonal |
| 细胞定位 | Membrane; Single-pass type I membrane protein. |
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