| 别名 | FGB;Fibrinogen beta chain |
| 基因名称 | FGB |
| 蛋白名称 | Fibrinogen beta chain |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P02675 |
| Mouse Swissprot No. | Q8K0E8 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000 |
| 参考分子量 | 55kDa |
| 预测分子量 | 56kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this gene is the beta component of fibrinogen , a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury , fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition , various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading , display vasoconstrictor and chemotactic activities , and are mitogens for several cell types. Mutations in this gene lead to several disorders , including afibrinogenemia , dysfibrinogenemia , hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq , Jun 2014] , |
| 细胞定位 | Secreted . |
| 纯化 | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Clonality | Monoclonal |
| 细胞定位 | Secreted . |
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