| 别名 | Coagulation factor X;Stuart factor;Stuart-Prower factor;[Cleaved into: Factor X light chain;Factor X heavy chain;Activated factor Xa heavy chain] |
| 基因名称 | F10 |
| 蛋白名称 | FA10 (light chain, Cleaved-Arg179) |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P00742 |
| Mouse Gene ID | 14058 |
| Mouse Swissprot No. | O88947 |
| Rat Gene ID | 29243 |
| Rat Swissprot No. | Q63207 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000 |
| 参考分子量 | 60kDa |
| 预测分子量 | 55kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | catalytic activity:Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin. ,function:Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va , calcium and phospholipid during blood clotting. ,online information:Factor X entry ,PTM:N- and O-glycosylated. ,PTM:The activation peptide is cleaved by factor IXa (in the intrinsic pathway) , or by factor VIIa (in the extrinsic pathway) . ,PTM:The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. ,PTM:The vitamin K-dependent , enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium. ,similarity:Belongs to the peptidase S1 family. ,similarity:Contains 1 Gla (gamma-carboxy-glutamate) domain. ,similarity:Contains 1 peptidase S1 domain. ,similarity:Contains 2 EGF-like domains. ,subunit:The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds. ,tissue specificity:Plasma; synthesized in the liver. , |
| 细胞定位 | Secreted. |
| 纯化 | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Clonality | Monoclonal |
| 细胞定位 | Secreted. |
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