| 别名 | USP11;UHX1;Ubiquitin carboxyl-terminal hydrolase 11;Deubiquitinating enzyme 11;Ubiquitin thioesterase 11;Ubiquitin-specific-processing protease 11 |
| 基因名称 | USP11 |
| 蛋白名称 | Ubiquitin carboxyl-terminal hydrolase 11 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P51784 |
| Mouse Gene ID | 236733 |
| Mouse Swissprot No. | Q99K46 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200 |
| 参考分子量 | 125kDa |
| 预测分子量 | 110kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Protein ubiquitination controls many intracellular processes , including cell cycle progression , transcriptional activation , and signal transduction. This dynamic process , involving ubiquitin conjugating enzymes and deubiquitinating enzymes , adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23 [provided by RefSeq , Jul 2008] , |
| 细胞定位 | Nucleus . Cytoplasm . Chromosome . Predominantly nuclear (PubMed:12084015 , PubMed:15314155) . Associates with chromatin (PubMed:20601937 , PubMed:20233726) . . |
| 纯化 | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Clonality | Monoclonal |
| 细胞定位 | Nucleus . Cytoplasm . Chromosome . Predominantly nuclear (PubMed:12084015 , PubMed:15314155) . Associates with chromatin (PubMed:20601937 , PubMed:20233726) . . |
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