| 别名 | REC8;REC8L1;Meiotic recombination protein REC8 homolog;Cohesin Rec8p |
| 基因名称 | REC8 |
| 蛋白名称 | Meiotic recombination protein REC8 homolog |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | O95072 |
| Mouse Swissprot No. | Q8C5S7 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000 |
| 参考分子量 | 83kDa |
| 预测分子量 | 63kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse , the homologous protein is a key component of the meiotic cohesion complex , which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants , encoding the same protein , have been found for this gene. [provided by RefSeq , Jul 2008] , |
| 细胞定位 | Nucleus . Chromosome . Chromosome , centromere . In meiotic chromosomes , localized along axial elements in prophase from the leptotene to diplotene stages. At later prophase stages , diakinesis and metaphase I , localized along interstitial axes of chromosomes including both centromere and arm regions. No longer detected in arm regions in anaphase I but persists on centromere regions until metaphase II. Localized to centromeres and spindle poles in endopolyploid tumor cells. . |
| 纯化 | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Clonality | Monoclonal |
| 细胞定位 | Nucleus . Chromosome . Chromosome , centromere . In meiotic chromosomes , localized along axial elements in prophase from the leptotene to diplotene stages. At later prophase stages , diakinesis and metaphase I , localized along interstitial axes of chromosomes including both centromere and arm regions. No longer detected in arm regions in anaphase I but persists on centromere regions until metaphase II. Localized to centromeres and spindle poles in endopolyploid tumor cells. . |
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