| 别名 | DCP1A;SMIF;mRNA-decapping enzyme 1A;Smad4-interacting transcriptional co-activator;Transcription factor SMIF |
| 基因名称 | DCP1A |
| 蛋白名称 | mRNA-decapping enzyme 1A |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | Q9NPI6 |
| Mouse Gene ID | 75901 |
| Mouse Swissprot No. | Q91YD3 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000 |
| 参考分子量 | 75kDa |
| 预测分子量 | 63kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex , which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq , Feb 2014] , |
| 细胞定位 | Cytoplasm , P-body . Nucleus . Co-localizes with NANOS3 in the processing bodies (By similarity) . Predominantly cytoplasmic , in processing bodies (PB) (PubMed:16364915) . Nuclear , after TGFB1 treatment. Translocation to the nucleus depends on interaction with SMAD4 (PubMed:11836524) . . |
| 纯化 | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Clonality | Monoclonal |
| 细胞定位 | Cytoplasm , P-body . Nucleus . Co-localizes with NANOS3 in the processing bodies (By similarity) . Predominantly cytoplasmic , in processing bodies (PB) (PubMed:16364915) . Nuclear , after TGFB1 treatment. Translocation to the nucleus depends on interaction with SMAD4 (PubMed:11836524) . . |
周一至周日 8:00-18:00
