| 别名 | Toll-like receptor 8;CD288 |
| 基因名称 | TLR8 |
| 蛋白名称 | Toll-like receptor 8 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | Q9NR97 |
| Mouse Swissprot No. | P58682 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000 |
| 参考分子量 | 140kDa |
| 预测分子量 | 120kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents , and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes , and lies in close proximity to another family member , TLR7 , on chromosome X. [provided by RefSeq , Jul 2008] , |
| 细胞定位 | Endosome membrane ; Single-pass type I membrane protein . Endosomal localization confers distinctive proteolytic processing. . |
| 纯化 | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Clonality | Monoclonal |
| 细胞定位 | Endosome membrane ; Single-pass type I membrane protein . Endosomal localization confers distinctive proteolytic processing. . |
周一至周日 8:00-18:00
