| 别名 | LYPLA1;APT1;LPL1;Acyl-protein thioesterase 1;APT-1;hAPT1;Lysophospholipase 1;Lysophospholipase I;LPL-I;LysoPLA I |
| 基因名称 | LYPLA1 |
| 蛋白名称 | Acyl-protein thioesterase 1 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | O75608 |
| Mouse Gene ID | 18777 |
| Mouse Swissprot No. | P97823 |
| Rat Gene ID | 25514 |
| Rat Swissprot No. | P70470 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000; |
| 参考分子量 | 24kDa |
| 预测分子量 | 25kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a member of the alpha/beta hydrolase superfamily. The encoded protein functions as a homodimer, exhibiting both depalmitoylating as well as lysophospholipase activity, and may be involved in Ras localization and signaling. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 4, 6, and 7. [provided by RefSeq, Jul 2013], |
| 细胞定位 | Cytoplasm . Cell membrane . Nucleus membrane . Endoplasmic reticulum . Shows predominantly a cytoplasmic localization with a weak expression in the cell membrane, nuclear membrane and endoplasmic reticulum. . |
| 功能 | Catalytic activity:Palmitoyl-protein + H(2)O = palmitate + protein.,Function:Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Also has low lysophospholipase activity.,similarity:Belongs to the AB hydrolase 2 family.,subunit:Homodimer., |
| Clonality | Monoclonal |
| 细胞定位 | Cytoplasm . Cell membrane . Nucleus membrane . Endoplasmic reticulum . Shows predominantly a cytoplasmic localization with a weak expression in the cell membrane, nuclear membrane and endoplasmic reticulum. . |
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