| 别名 | CTPCT;PCYT1 |
| 基因名称 | PCYT1A |
| 蛋白名称 | Choline-phosphate cytidylyltransferase A (CCT-alpha) (CTP:phosphocholine cytidylyltransferase A) (CCT A) (CT A) (Phosphorylcholine transferase A) |
| 推荐应用 | |
| 反应物种 | Human,Mouse |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P49585 |
| Mouse Swissprot No. | P49586 |
| Rat Swissprot No. | P19836 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000; |
| 参考分子量 | 42kDa |
| 预测分子量 | 42kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene belongs to the cytidylyltransferase family and is involved in the regulation of phosphatidylcholine biosynthesis. Mutations in this gene are associated with spondylometaphyseal dysplasia with cone-rod dystrophy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015], |
| 细胞定位 | Cytoplasm, cytosol . Membrane ; Peripheral membrane protein . Endoplasmic reticulum . Nucleus . It can interconvert between an inactive cytosolic form and an active membrane-bound form. . |
| 功能 | Catalytic activity:CTP + choline phosphate = diphosphate + CDP-choline.,enzyme regulation:By phosphorylation.,Function:Controls phosphatidylcholine synthesis.,pathway:Phospholipid metabolism; phosphatidylcholine biosynthesis; phosphatidylcholine from phosphocholine: step 1/2.,PTM:The serine residues of the C-terminus are phosphorylated. The inactive soluble form is stabilized by phosphorylation, the active membrane bound form is promoted by anionic lipids or diacylglycerol, and is stabilized by dephosphorylation.,similarity:Belongs to the cytidylyltransferase family.,subcellular location:It can interconvert between an inactive cytosolic form and an active membrane-bound form.,subunit:Homodimer; disulfide-linked., |
| Clonality | Monoclonal |
| 细胞定位 | Cytoplasm, cytosol . Membrane ; Peripheral membrane protein . Endoplasmic reticulum . Nucleus . It can interconvert between an inactive cytosolic form and an active membrane-bound form. . |
周一至周日 8:00-18:00
