| 别名 | RNASE3;ECP;RNS3;Eosinophil cationic protein;ECP;Ribonuclease 3;RNase 3 |
| 基因名称 | RNASE3 |
| 蛋白名称 | Eosinophil cationic protein |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P12724 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000;WB 1:1000-1:5000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000; |
| 参考分子量 | 18kDa |
| 预测分子量 | 18kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria [provided by RefSeq, Oct 2014], |
| 细胞定位 | Secreted. Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus. |
| 功能 | Disease:Induces the neurotoxic effect known as the Gordon phenomenon.,Function:Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity.,similarity:Belongs to the pancreatic ribonuclease family.,subcellular location:Matrix of eosinophil's large specific granule., |
| Clonality | Monoclonal |
| 细胞定位 | Secreted. Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus. |