| 别名 | CPT1 |
| 基因名称 | CPT2 |
| 蛋白名称 | Carnitine O-palmitoyltransferase 2, mitochondrial (Carnitine palmitoyltransferase II) (CPT II) |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P23786 |
| Mouse Gene ID | 12896 |
| Mouse Swissprot No. | P52825 |
| Rat Gene ID | 12896 |
| Rat Swissprot No. | P18886 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000; |
| 参考分子量 | 68kDa |
| 预测分子量 | 74kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this gene is a nuclear protein which is transported to the mitochondrial inner membrane. Together with carnitine palmitoyltransferase I, the encoded protein oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders. [provided by RefSeq, Jul 2008] |
| 细胞定位 | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. |
| 功能 | Involved in the intramitochondrial synthesis of acylcarnitines from accumulated acyl-CoA metabolites (PubMed:20538056, PubMed:24780397). Reconverts acylcarnitines back into the respective acyl-CoA esters that can then undergo beta-oxidation, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Active with medium (C8-C12) and long-chain (C14-C18) acyl-CoA esters (PubMed:20538056). |
| Clonality | Monoclonal |
| 细胞定位 | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. |
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