| 别名 | GUCY1A3;GUC1A3;GUCSA3;GUCY1A1;Guanylate cyclase soluble subunit alpha-3;GCS-alpha-3;GCS-alpha-1;Soluble guanylate cyclase large subunit |
| 基因名称 | GUCY1A3 |
| 蛋白名称 | Guanylate cyclase soluble subunit alpha-3 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | Q02108 |
| Mouse Gene ID | 60596 |
| Mouse Swissprot No. | Q9ERL9 |
| Rat Swissprot No. | P19686 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:1000-1:5000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000; |
| 参考分子量 | 70kDa |
| 预测分子量 | 77kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012], |
| 细胞定位 | Cytoplasm . |
| 功能 | Catalytic activity:GTP = 3',5'-cyclic GMP + diphosphate.,enzyme regulation:Activated by nitric oxide in the presence of magnesium or manganese ions.,miscellaneous:There are two types of guanylate cyclases: soluble forms and membrane-associated receptor forms.,similarity:Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.,similarity:Contains 1 guanylate cyclase domain.,subunit:Heterodimer of an alpha and a beta chain., |
| Clonality | Monoclonal |
| 细胞定位 | Cytoplasm . |
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