货号：GZ9306
PRDM1;BLIMP1;PR domain zinc finger protein 1;BLIMP-1;Beta-interferon gene positive regulatory domain I-binding factor;PR domain-containing protein 1;Positive regulatory domain I-binding factor 1;PRDI-BF1;PRDI-binding factor 1
| 别名 | PRDM1;BLIMP1;PR domain zinc finger protein 1;BLIMP-1;Beta-interferon gene positive regulatory domain I-binding factor;PR domain-containing protein 1;Positive regulatory domain I-binding factor 1;PRDI-BF1;PRDI-binding factor 1 |
| 基因名称 | PRDM1 |
| 蛋白名称 | PR domain zinc finger protein 1 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | O75626 |
| Mouse Gene ID | 12142 |
| Mouse Swissprot No. | Q60636 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:100-1:200;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000; |
| 参考分子量 | 90-100kDa |
| 预测分子量 | 92kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Nucleus . Cytoplasm . |
| 功能 | Function:Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells.,similarity:Contains 1 SET domain.,similarity:Contains 4 C2H2-type zinc fingers.,subunit:Interacts with PRMT5., |
| Clonality | Monoclonal |
| 细胞定位 | Nucleus . Cytoplasm . |
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