| 别名 | CLDN2;PSEC0059;SP82;Claudin-2;SP82 |
| 基因名称 | CLDN2 |
| 蛋白名称 | Claudin-2 |
| 推荐应用 | |
| 反应物种 | Human,Mouse |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P57739 |
| Mouse Gene ID | 12738 |
| Mouse Swissprot No. | O88552 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:500;WB 1:10000-1:50000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000; |
| 参考分子量 | 20kDa |
| 预测分子量 | 25kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010], |
| 细胞定位 | Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein . |
| 功能 | Function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.,similarity:Belongs to the claudin family.,subunit:Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN1, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3., |
| Clonality | Monoclonal |
| 细胞定位 | Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein . |
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