| 别名 | Receptor-interacting serine/threonine-protein kinase 3;RIP-like protein kinase 3;Receptor-interacting protein 3;RIP-3;RIP3 |
| 基因名称 | RIPK3 |
| 蛋白名称 | Receptor-interacting serine/threonine-protein kinase 3 (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | Q9Y572 |
| Mouse Swissprot No. | Q9QZL0 |
| Rat Gene ID | 246240 |
| Rat Swissprot No. | Q9Z2P5 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000, WB 1:2000-1:10000, IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200 |
| 参考分子量 | 57kDa |
| 预测分子量 | 57kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Cytoplasm, cytosol . Nucleus . Mainly cytoplasmic. Present in the nucleus in response to influenza A virus (IAV) infection. . |
| Clonality | Monoclonal |
| 细胞定位 | Cytoplasm, cytosol . Nucleus . Mainly cytoplasmic. Present in the nucleus in response to influenza A virus (IAV) infection. . |