| 别名 | LCP2;Lymphocyte cytosolic protein 2;SH2 domain-containing leukocyte protein of 76 kDa;SLP-76 tyrosine phosphoprotein;SLP76 |
| 基因名称 | LCP2 |
| 蛋白名称 | Lymphocyte cytosolic protein 2 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | Q13094 |
| Mouse Gene ID | 16822 |
| Mouse Swissprot No. | Q60787 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:100-1:200, WB 1:2000-1:10000, IF 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 70kDa |
| 预测分子量 | 60kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T c |
| 细胞定位 | Cytoplasm . |
| Clonality | Monoclonal |
| 细胞定位 | Cytoplasm . |
周一至周日 8:00-18:00
