货号：GZ9237
AW212142;dual specificity mitogen activated protein kinase kinase 3;Dual specificity mitogen activated protein kinase kinase 6;Dual specificity mitogen-activated protein kinase kinase 3;MAP kinase kinase 3;MAP kinase kinase 6;map2k3;MAP2K6;MAPK ERK kinase 3;MAPK/ERK kinase 3;MAPK/ERK kinase 6;MAPKK 3;MAPKK 6;MAPKK3;MAPKK6;MEK 3;MEK 6;MEK3;Mitogen activated protein kinase kinase 3;Mitogen activated protein kinase kinase 6;MKK 3;MKK3;MKK6;mMKK3b;MP2K3_HUMAN;PRKMK 3;PRKMK3;PRKMK6;Protein kinase, mitogen activated, kinase 6;MAP kinase kinase 6;protein kinase, mitogen-activated, kinase 3;SAPK kinase 2;SAPKK 2;SAPKK 3;SAPKK-2;SAPKK2;SAPKK3;Stress activated protein kinase kinase 2;Stress activated protein kinase kinase 3;Stress-activated protein kinase kinase 2.
| 别名 | AW212142;dual specificity mitogen activated protein kinase kinase 3;Dual specificity mitogen activated protein kinase kinase 6;Dual specificity mitogen-activated protein kinase kinase 3;MAP kinase kinase 3;MAP kinase kinase 6;map2k3;MAP2K6;MAPK ERK kinase 3;MAPK/ERK kinase 3;MAPK/ERK kinase 6;MAPKK 3;MAPKK 6;MAPKK3;MAPKK6;MEK 3;MEK 6;MEK3;Mitogen activated protein kinase kinase 3;Mitogen activated protein kinase kinase 6;MKK 3;MKK3;MKK6;mMKK3b;MP2K3_HUMAN;PRKMK 3;PRKMK3;PRKMK6;Protein kinase, mitogen activated, kinase 6;MAP kinase kinase 6;protein kinase, mitogen-activated, kinase 3;SAPK kinase 2;SAPKK 2;SAPKK 3;SAPKK-2;SAPKK2;SAPKK3;Stress activated protein kinase kinase 2;Stress activated protein kinase kinase 3;Stress-activated protein kinase kinase 2. |
| 基因名称 | MAP2K3 |
| 蛋白名称 | Serine protease HTRA2 mitochondrial |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P46734;P52564 |
| Mouse Gene ID | 26397;26399 |
| Mouse Swissprot No. | O09110;P70236 |
| 特异性 | MKK3 (Phospho Ser189)/MKK6 (Phospho Ser207) Antibody detects endogenous levels of MKK3/MEK6 protein only when phosphorylated at S189/S207.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):IHrDV/VDsVA |
| 稀释度 | IHC-P 1:100-1:500, WB 1:1000-1:5000, IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200 |
| 参考分子量 | 39kDa,37kDa |
| 预测分子量 | 39kDa,37kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Binds to microtubules. |
| Clonality | Monoclonal |
| 细胞定位 | Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Binds to microtubules. |
周一至周日 8:00-18:00