| 别名 | Tumor necrosis factor receptor superfamily member 11A;Osteoclast differentiation factor receptor;ODFR;Receptor activator of NF-KB;CD antigen CD265;RANK |
| 基因名称 | TNFRSF11A |
| 蛋白名称 | Tumor necrosis factor receptor superfamily member 11A (Osteoclast differentiation factor receptor) (ODFR) (Receptor activator of NF-KB) (CD antigen CD265) |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | Q9Y6Q6 |
| Mouse Gene ID | 21934 |
| Mouse Swissprot No. | O35305 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000, WB 1:10000-1:50000, IF 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 70kDa |
| 预测分子量 | 66kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012], |
| 细胞定位 | [Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform RANK-e5a]: Cell membrane ; Single-pass type I membrane protein . |
| Clonality | Monoclonal |
| 细胞定位 | [Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform RANK-e5a]: Cell membrane ; Single-pass type I membrane protein . |
周一至周日 8:00-18:00
