| 别名 | TSC2;TSC4;Tuberin;Tuberous sclerosis 2 protein |
| 基因名称 | TSC2 |
| 蛋白名称 | Tuberin |
| 推荐应用 | |
| 反应物种 | Human,Mouse |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P49815 |
| Mouse Swissprot No. | Q61037 |
| Rat Gene ID | 24855 |
| Rat Swissprot No. | P49816 |
| 特异性 | Tuberin (Phospho Thr1462) Antibody detects endogenous levels of Tuberin protein only when phosphorylated at T1462.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):GYtIS |
| 稀释度 | IHC-P 1:100-1:200, WB 1:2000-1:10000, IF 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 201kDa |
| 预测分子量 | 201kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Cytoplasm. Membrane; Peripheral membrane protein. At steady state found in association with membranes. |
| Clonality | Monoclonal |
| 细胞定位 | Cytoplasm. Membrane; Peripheral membrane protein. At steady state found in association with membranes. |
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