| 别名 | TIMP1;CLGI;TIMP;Metalloproteinase inhibitor 1;Erythroid-potentiating activity;EPA;Fibroblast collagenase inhibitor;Collagenase inhibitor;Tissue inhibitor of metalloproteinases 1;TIMP-1 |
| 基因名称 | TIMP1 |
| 蛋白名称 | Metalloproteinase inhibitor 1 |
| 推荐应用 | |
| 反应物种 | Mouse |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P01033 |
| Mouse Gene ID | 21857 |
| Mouse Swissprot No. | P12032 |
| Rat Gene ID | 116510 |
| Rat Swissprot No. | P30120 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500-1:2000, IF 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 26kDa |
| 预测分子量 | 23kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Secreted . |
| Clonality | Monoclonal |
| 细胞定位 | Secreted . |
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