| 别名 | AGTR1;AGTR1A;AGTR1B;AT2R1;AT2R1B;Type-1 angiotensin II receptor;AT1AR;AT1BR;Angiotensin II type-1 receptor;AT1;AGTR1A;AGTR1B;AT2R1;AT2R1B |
| 基因名称 | AGTR1 |
| 蛋白名称 | Type-1 angiotensin II receptor |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P30556 |
| Rat Gene ID | 24180 |
| Rat Swissprot No. | P25095 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500-1:2000, IF 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 36kDa |
| 预测分子量 | 41kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012], |
| 细胞定位 | Cell membrane ; Multi-pass membrane protein . |
| Clonality | Monoclonal |
| 细胞定位 | Cell membrane ; Multi-pass membrane protein . |
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