| 别名 | NEFM;NEF3;NFM;Neurofilament medium polypeptide;NF-M;160 kDa neurofilament protein;Neurofilament 3;Neurofilament triplet M protein |
| 基因名称 | NEFM |
| 蛋白名称 | Neurofilament medium polypeptide |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P07197 |
| Mouse Swissprot No. | P08553 |
| 特异性 | NF-M (Phospho Ser614/Ser619) Antibody detects endogenous levels of NF-M protein only when phosphorylated at S614/S619.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):KAkSP/VPkSP |
| 稀释度 | IHC-P 1:200-1:1000, WB 1:500-1:2000, IF 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 180kDa |
| 预测分子量 | 103kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | neurofilament, medium polypeptide(NEFM) Homo sapiens Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008], |
| 细胞定位 | Cytoplasm, cytoskeleton . Cell projection, axon . |
| Clonality | Monoclonal |
| 细胞定位 | Cytoplasm, cytoskeleton . Cell projection, axon . |
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