货号：GZ9171
CHUK;IKKA;TCF16;Inhibitor of nuclear factor kappa-B kinase subunit alpha;I-kappa-B kinase alpha;IKK-A;IKK-alpha;IkBKA;IkappaB kinase;Conserved helix-loop-helix ubiquitous kinase;I-kappa-B kinase 1;IKK1;Nuclear factor NF-kappa-B
| 别名 | CHUK;IKKA;TCF16;Inhibitor of nuclear factor kappa-B kinase subunit alpha;I-kappa-B kinase alpha;IKK-A;IKK-alpha;IkBKA;IkappaB kinase;Conserved helix-loop-helix ubiquitous kinase;I-kappa-B kinase 1;IKK1;Nuclear factor NF-kappa-B |
| 基因名称 | CHUK/IKBKB |
| 蛋白名称 | Inhibitor of nuclear factor kappa-B kinase subunit alpha |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | O15111;O14920 |
| Mouse Gene ID | 16150 |
| Rat Gene ID | 84351 |
| Rat Swissprot No. | Q9QY78 |
| 特异性 | IKK-α/β (Phospho Ser176/180) antibody detects endogenous levels of IKKα/β only when phosphorylated at S176/S180.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):QGsLC/CTsFV |
| 稀释度 | IHC-P 1:200-1:1000, WB 1:1000-1:5000, IF 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 80kDa |
| 预测分子量 | 85kDa,87kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Cytoplasm . Nucleus . Shuttles between the cytoplasm and the nucleus. |
| Clonality | Monoclonal |
| 细胞定位 | Cytoplasm . Nucleus . Shuttles between the cytoplasm and the nucleus. |
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