| 别名 | CAPN2;CANPL2;Calpain-2 catalytic subunit;Calcium-activated neutral proteinase 2;CANP 2;Calpain M-type;Calpain large polypeptide L2;Calpain-2 large subunit;Millimolar-calpain;M-calpain |
| 基因名称 | CAPN2 |
| 蛋白名称 | Calpain-2 catalytic subunit |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P17655 |
| Mouse Gene ID | 12334 |
| Mouse Swissprot No. | O08529 |
| Rat Gene ID | 29154 |
| Rat Swissprot No. | Q07009 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:1000-1:20000, IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200 |
| 参考分子量 | 75kDa |
| 预测分子量 | 80kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009], |
| 细胞定位 | Cytoplasm. Cell membrane. Translocates to the plasma membrane upon Ca(2+) binding. |
| Clonality | Monoclonal |
| 细胞定位 | Cytoplasm. Cell membrane. Translocates to the plasma membrane upon Ca(2+) binding. |