| 别名 | CCR2;CMKBR2;C-C chemokine receptor type 2;C-C CKR-2;CC-CKR-2;CCR-2;CCR2;Monocyte chemoattractant protein 1 receptor;MCP-1-R;CD192 |
| 基因名称 | CCR2 |
| 蛋白名称 | C-C chemokine receptor type 2 |
| 推荐应用 | |
| 反应物种 | Mouse |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P41597 |
| Mouse Gene ID | 12772 |
| Mouse Swissprot No. | P51683 |
| Rat Gene ID | 60463 |
| Rat Swissprot No. | O55193 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:1000-1:20000, IF 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 43kDa |
| 预测分子量 | 42kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009], |
| 细胞定位 | Cell membrane ; Multi-pass membrane protein . The chemoattractant receptors are distributed throughout the cell surface; after stimulation with a ligand, such as CCL2, they are rapidly recruited into microdomain clusters at the cell membrane. . |
| Clonality | Monoclonal |
| 细胞定位 | Cell membrane ; Multi-pass membrane protein . The chemoattractant receptors are distributed throughout the cell surface; after stimulation with a ligand, such as CCL2, they are rapidly recruited into microdomain clusters at the cell membrane. . |
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