| 别名 | Tumor necrosis factor receptor superfamily member 10B;Death receptor 5;TNF-related apoptosis-inducing ligand receptor 2;TRAIL receptor 2;TRAIL-R2;CD antigen CD262;DR5;KILLER;TRAILR2;TRICK2;ZTNFR9;UNQ160/PRO186 |
| 基因名称 | TNFRSF10B |
| 蛋白名称 | Tumor necrosis factor receptor superfamily member 10B |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | O14763 |
| Mouse Gene ID | 21933 |
| Mouse Swissprot No. | Q9QZM4 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200 |
| 参考分子量 | 40kDa,49kDa |
| 预测分子量 | 49kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009], |
| 细胞定位 | Membrane; Single-pass type I membrane protein. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 细胞定位 | Membrane; Single-pass type I membrane protein. |
周一至周日 8:00-18:00
