| 别名 | Speckle-type POZ protein;HIB homolog 1;Roadkill homolog 1; |
| 基因名称 | SPOP |
| 蛋白名称 | SPOP |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | O43791 |
| Mouse Gene ID | 20747 |
| Mouse Swissprot No. | Q6ZWS8 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 42kDa |
| 预测分子量 | 42kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Nucleus . Nucleus speckle . |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 细胞定位 | Nucleus . Nucleus speckle . |
周一至周日 8:00-18:00
