| 别名 | ITGA6;Integrin alpha-6;CD49 antigen-like family member F;VLA-6;CD49f |
| 基因名称 | ITGA6 |
| 蛋白名称 | Integrin alpha-6 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P23229 |
| Mouse Swissprot No. | Q61739 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:100-1:400, WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 127kDa |
| 预测分子量 | 127kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | integrin subunit alpha 6(ITGA6) Homo sapiens The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015], |
| 细胞定位 | Cell membrane ; Single-pass type I membrane protein . Cell membrane ; Lipid-anchor . |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 细胞定位 | Cell membrane ; Single-pass type I membrane protein . Cell membrane ; Lipid-anchor . |
周一至周日 8:00-18:00
