| 别名 | EIF4EBP1;Eukaryotic translation initiation factor 4E-binding protein 1;4E-BP1;eIF4E-binding protein 1;Phosphorylated heat- and acid-stable protein regulated by insulin 1;PHAS-I |
| 基因名称 | EIF4EBP1 |
| 蛋白名称 | Eukaryotic translation initiation factor 4E-binding protein 1 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | Q13541 |
| Mouse Gene ID | 13685 |
| Mouse Swissprot No. | Q60876 |
| Rat Gene ID | 116636 |
| Rat Swissprot No. | Q62622 |
| 特异性 | 4E-BP1 (Phospho Thr70) Antibody detects endogenous levels of 4E-BP1 protein only when phosphorylated at T70.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):TKtPP |
| 稀释度 | IHC-P 1:200-1:1000, WB 1:500-1:2000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 15-20kDa |
| 预测分子量 | 13kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Nucleus |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 细胞定位 | Nucleus |
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