| 别名 | LAT;Linker for activation of T-cells family member 1;36 kDa phospho-tyrosine adapter protein;pp36;p36-38 |
| 基因名称 | LAT |
| 蛋白名称 | Linker for activation of T-cells family member 1 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | O43561 |
| Mouse Gene ID | 16797 |
| Mouse Swissprot No. | O54957 |
| Rat Gene ID | 81511 |
| Rat Swissprot No. | O70601 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000, WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200 |
| 参考分子量 | 36kDa |
| 预测分子量 | 28kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Cell membrane ; Single-pass type III membrane protein . Present in lipid rafts. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 细胞定位 | Cell membrane ; Single-pass type III membrane protein . Present in lipid rafts. |
周一至周日 8:00-18:00
