| 别名 | PDK1;PDHK1;[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1;mitochondrial;Pyruvate dehydrogenase kinase isoform 1 |
| 基因名称 | PDK1 |
| 蛋白名称 | [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1 mitochondrial |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | Q15118 |
| Mouse Gene ID | 228026 |
| Mouse Swissprot No. | Q8BFP9 |
| Rat Swissprot No. | Q63065 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200 |
| 参考分子量 | 49kDa |
| 预测分子量 | 49kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013], |
| 细胞定位 | Mitochondrion matrix . |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 细胞定位 | Mitochondrion matrix . |