| 别名 | GRB2;ASH;Growth factor receptor-bound protein 2;Adapter protein GRB2;Protein Ash;SH2/SH3 adapter GRB2 |
| 基因名称 | GRB2 |
| 蛋白名称 | Growth factor receptor-bound protein 2 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P62993 |
| Mouse Gene ID | 14784 |
| Mouse Swissprot No. | Q60631 |
| Rat Gene ID | 81504 |
| Rat Swissprot No. | P62994 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000, WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200 |
| 参考分子量 | 25kDa |
| 预测分子量 | 25kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Nucleus . Cytoplasm . Endosome . Golgi apparatus . |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 细胞定位 | Nucleus . Cytoplasm . Endosome . Golgi apparatus . |