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首页 > 产品中心 > 抗体系列 > 一抗

货号:GZ8972

Lyn (14H6) Rabbit Monoclonal Antibody

LYN;JTK8;Tyrosine-protein kinase Lyn;Lck/Yes-related novel protein tyrosine kinase;V-yes-1 Yamaguchi sarcoma viral related oncogene homolog;p53Lyn;p56Lyn

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别名 LYN;JTK8;Tyrosine-protein kinase Lyn;Lck/Yes-related novel protein tyrosine kinase;V-yes-1 Yamaguchi sarcoma viral related oncogene homolog;p53Lyn;p56Lyn
基因名称 LYN
蛋白名称 Tyrosine-protein kinase Lyn
推荐应用
反应物种 Human,Mouse,Rat
存储缓冲液 PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Human Swissprot No. P07948
Mouse Gene ID 17096
Mouse Swissprot No. P25911
Rat Gene ID 81515
Rat Swissprot No. Q07014
特异性 Endogenous
稀释度 WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000
参考分子量 59kDa
预测分子量 59kDa
运输及保存条件 Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles
宿主 Rabbit
同种型 IgG,Kappa
背景介绍 This gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011],
细胞定位 Cell membrane. Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus. Membrane ; Lipid-anchor . Accumulates in the nucleus by inhibition of CRM1-mediated nuclear export. Nuclear accumulation is increased by inhibition of its kinase activity. The trafficking from the Golgi apparatus to the plasma membrane occurs in a kinase domain-dependent but kinase activity independent manner and is mediated by exocytic vesicular transport. Detected on plasma membrane lipid rafts.
纯化 Protein A
Clonality Monoclonal
细胞定位 Cell membrane. Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus. Membrane ; Lipid-anchor . Accumulates in the nucleus by inhibition of CRM1-mediated nuclear export. Nuclear accumulation is increased by inhibition of its kinase activity. The trafficking from the Golgi apparatus to the plasma membrane occurs in a kinase domain-dependent but kinase activity independent manner and is mediated by exocytic vesicular transport. Detected on plasma membrane lipid rafts.

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