| 别名 | IGF1R;Insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;IGF-I receptor;CD antigen CD221 |
| 基因名称 | IGF1R |
| 蛋白名称 | Insulin-like growth factor 1 receptor |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P08069 |
| Mouse Gene ID | 16001 |
| Mouse Swissprot No. | Q60751 |
| Rat Gene ID | 25718 |
| Rat Swissprot No. | P24062 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200 |
| 参考分子量 | 95kDa |
| 预测分子量 | 154kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014], |
| 细胞定位 | Cell membrane ; Single-pass type I membrane protein . |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 细胞定位 | Cell membrane ; Single-pass type I membrane protein . |
周一至周日 8:00-18:00
