| 别名 | UCP2;SLC25A8;Mitochondrial uncoupling protein 2;UCP 2;Solute carrier family 25 member 8;UCPH |
| 基因名称 | UCP2 |
| 蛋白名称 | Mitochondrial uncoupling protein 2 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P55851 |
| Mouse Gene ID | 22228 |
| Mouse Swissprot No. | P70406 |
| Rat Gene ID | 54315 |
| Rat Swissprot No. | P56500 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:100-1:500, WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 33kDa |
| 预测分子量 | 33kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'. [prov |
| 细胞定位 | Mitochondrion inner membrane; Multi-pass membrane protein. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 细胞定位 | Mitochondrion inner membrane; Multi-pass membrane protein. |
周一至周日 8:00-18:00
