| 别名 | HRMT1L5;IBP72;JBP1;SKB1 |
| 基因名称 | PRMT5 |
| 蛋白名称 | Protein arginine N-methyltransferase 5 (72 kDa ICln-binding protein) (Histone-arginine N-methyltransferase PRMT5) (Jak-binding protein 1) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog) (SKB1Hs) [Cleaved into: Protein arginine N-methyltransferase 5, N-terminally processed] |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | O14744 |
| Mouse Swissprot No. | Q8CIG8 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:500-1:2000, WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200 |
| 参考分子量 | 70kDa |
| 预测分子量 | 73kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015], |
| 细胞定位 | Cytoplasm . Nucleus . Chromosome . Golgi apparatus . Localizes to promoter regions of target genes on chromosomes. . |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 细胞定位 | Cytoplasm . Nucleus . Chromosome . Golgi apparatus . Localizes to promoter regions of target genes on chromosomes. . |
周一至周日 8:00-18:00
