| 别名 | Neurofilament light polypeptide;NF-L;68 kDa neurofilament protein;Neurofilament triplet L protein;NF68;NFL |
| 基因名称 | NEFL |
| 蛋白名称 | Neurofilament light polypeptide;NF-L;Neurofilament triplet L protein;68 kDa neurofilament protein; |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P07196 |
| Mouse Gene ID | 18039 |
| Mouse Swissprot No. | P08551 |
| Rat Gene ID | 83613 |
| Rat Swissprot No. | P19527 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:2000-1:10000, WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200, |
| 参考分子量 | 68kDa |
| 预测分子量 | 62kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008], |
| 细胞定位 | Cytoplasmic |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 细胞定位 | Cytoplasmic |
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