货号：GZ8825
MAP2K7;JNKK2;MEK7;MKK7;PRKMK7;SKK4;Dual specificity mitogen-activated protein kinase kinase 7;MAP kinase kinase 7;MAPKK 7;JNK-activating kinase 2;MAPK/ERK kinase 7;MEK 7;Stress-activated protein kinase kinase 4;SAPK kinase 4;S
| 别名 | MAP2K7;JNKK2;MEK7;MKK7;PRKMK7;SKK4;Dual specificity mitogen-activated protein kinase kinase 7;MAP kinase kinase 7;MAPKK 7;JNK-activating kinase 2;MAPK/ERK kinase 7;MEK 7;Stress-activated protein kinase kinase 4;SAPK kinase 4;S |
| 基因名称 | MAP2K7 |
| 蛋白名称 | Dual specificity mitogen-activated protein kinase kinase 7 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | O14733 |
| Mouse Gene ID | 26400 |
| Mouse Swissprot No. | Q8CE90 |
| Rat Gene ID | 363855 |
| Rat Swissprot No. | Q4KSH7 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000, WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 48kDa |
| 预测分子量 | 48kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014], |
| 细胞定位 | Nucleus. Cytoplasm . |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 细胞定位 | Nucleus. Cytoplasm . |
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