货号：GZ8823
ATP2A2;ATP2B;Sarcoplasmic/endoplasmic reticulum calcium ATPase 2;SERCA2;SR Ca;2+;-ATPase 2;Calcium pump 2;Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform;Endoplasmic reticulum class 1/2 Ca;2+;ATPase
| 别名 | ATP2A2;ATP2B;Sarcoplasmic/endoplasmic reticulum calcium ATPase 2;SERCA2;SR Ca;2+;-ATPase 2;Calcium pump 2;Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform;Endoplasmic reticulum class 1/2 Ca;2+;ATPase |
| 基因名称 | ATP2A2 |
| 蛋白名称 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P16615 |
| Mouse Gene ID | 11938 |
| Mouse Swissprot No. | O55143 |
| Rat Gene ID | 29693 |
| Rat Swissprot No. | P11507 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000, WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 140kDa |
| 预测分子量 | 115kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2008], |
| 细胞定位 | Endoplasmic reticulum membrane ; Multi-pass membrane protein . Sarcoplasmic reticulum membrane ; Multi-pass membrane protein . |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 细胞定位 | Endoplasmic reticulum membrane ; Multi-pass membrane protein . Sarcoplasmic reticulum membrane ; Multi-pass membrane protein . |
周一至周日 8:00-18:00
